Co-crystallization of an organic solid and a tetraaryladamantane at room temperature

• Fabian Rami,
• Jan Nowak,
• Felix Krupp,
• Wolfgang Frey and
• Clemens Richert

Beilstein J. Org. Chem. 2021, 17, 1476–1480, doi:10.3762/bjoc.17.103

• crystal lattice set up by a larger compound or crystalline complex [8][9]. For some medium-size molecules, supercritical fluids have been used to obtain co-crystals [10]. Other co-crystals were obtained by encapsulating guest molecules in pre-planned frameworks, set up with organic salts [11]. At this

A comprehensive review of flow chemistry techniques tailored to the flavours and fragrances industries

• Guido Gambacorta,
• James S. Sharley and
• Ian R. Baxendale

Beilstein J. Org. Chem. 2021, 17, 1181–1312, doi:10.3762/bjoc.17.90

Supercritical carbon dioxide: a solvent like no other

• Jocelyn Peach and
• Julian Eastoe

Beilstein J. Org. Chem. 2014, 10, 1878–1895, doi:10.3762/bjoc.10.196

• and production of toxic reagents and products, avoidance of auxiliary substances where possible, and minimization of the energy requirements needed for the process, under this umbrella [2]. Attention has been drawn to the potential surrounding by the use of supercritical fluids and carbon dioxide in

• food products [14] as well as already being an established system for numerous processes [16], including extractions [17], nanoparticle production and modification [18][19][20][21] and polymer processing [22][23][24][25]. Supercritical fluids also make appealing solvents due to the opportunities for

Continuous-flow Heck synthesis of 4-methoxybiphenyl and methyl 4-methoxycinnamate in supercritical carbon dioxide expanded solvent solutions

• Phei Li Lau,
• Ray W. K. Allen and
• Peter Styring

Beilstein J. Org. Chem. 2013, 9, 2886–2897, doi:10.3762/bjoc.9.325

• biphasic mode using a mixture of solvents, such as ethylene glycol and toluene [8]. The drive to carry out reactions in environmentally benign media also led to studies being carried out in “green” (environmentally friendly) solvents, such as aqueous media, some supercritical fluids (SCFs), ionic liquids

Impact of cyclodextrins on the behavior of amphiphilic ligands in aqueous organometallic catalysis

• Hervé Bricout,
• Estelle Léonard,
• Christophe Len,
• David Landy,
• Frédéric Hapiot and
• Eric Monflier

Beilstein J. Org. Chem. 2012, 8, 1479–1484, doi:10.3762/bjoc.8.167

• products. Traditional solvents have especially been incriminated due to the pollution problems they raise. Thus, in the context of increased awareness about environmental safety, nonconventional media appeared to be a promising alternative to toxic solvents. The use of supercritical fluids, ionic liquids

Efficient and selective chemical transformations under flow conditions: The combination of supported catalysts and supercritical fluids

• M. Isabel Burguete,
• Eduardo García-Verdugo and
• Santiago V. Luis

Beilstein J. Org. Chem. 2011, 7, 1347–1359, doi:10.3762/bjoc.7.159

• on solid supports or in liquid phases and supercritical fluids (scFs), to develop selective and enantioselective chemical transformations under continuous and semi-continuous flow conditions. The results presented have been selected to highlight how the combined use of those two elements can

• -supported systems; supercritical fluids; Review Introduction An ideal synthetic process, combining the concepts of classical synthetic chemistry and those of the more recently developed green chemistry, would be one that provides complete conversions of the substrates and that would give place to high

• mind for their possible implementation. Supercritical fluids exhibit unique properties that offer the opportunity to manipulate, as required, the parameters of the reaction environment, such as density, viscosity, diffusivity or surface tension, continuously from gaslike to liquid-like properties

Asymmetric reactions in continuous flow

• Xiao Yin Mak,
• Paola Laurino and
• Peter H. Seeberger

Beilstein J. Org. Chem. 2009, 5, No. 19, doi:10.3762/bjoc.5.19

• conditions as well as in supercritical carbon dioxide (scCO2), as means of creating a more ‘environmentally-friendly’ process [45]. Under the solventless or scCO2 flow conditions, the productivity of the catalyst was observed to be much higher. The use of supercritical fluids, in particular scCO2, as an